István Köteles

Postdoctoral Fellow

istvan.koteles@gu.se

EDUCATION & EXPERIENCE

2022-present: Postdoctoral Work

University of Gothenburg, Sweden

2015-2022: Ph.D. in Organic and Medicinal Chemistry

Semmelweis University, Hungary

2010-2015: M.Sc. in Pharmaceutical Sciences

Semmelweis University, Hungary

RESEARCH INTERESTS

I am upmost interested in medicinal chemistry and the application of various organic chemistry methods in the development of new pharmaceutical compounds. Currently I am working on the synthesis of allosteric modulators for pyruvate kinase liver isozyme utilizing fragment based drug design.

PUBLICATIONS

Mirzahosseini A, Molaei M, Mazák K, Pálla T, Köteles I, Varró N, Mándity I, Noszál B. Species-specific acid-base characterization of carnosine and homocarnosine using nuclear magnetic resonance. Chem. Phys. Lett., 2022, 808, 140128.

Köteles I, Mazák K, Tóth G, Horváth P, Kiss E, Tűz B, Hosztafi S. Synthesis of 3-O-Carboxyalkyl Morphine Derivatives and Characterization of Their Acid-Base Properties. Chem. Biodiversity, 2021, 18, e2100135

Fejős I, Tóth G, Várnai B, Szabó ZI, Köteles I, Malanga M, Béni Sz. Enantioseparation of solriamfetol and its major impurity phenylalaninol by capillary electrophoresis using sulfated gamma cyclodextrin. Electrophoresis, 2021, 42, 1818-1825.

Köteles I, Mazák K, Tóth G, Tűz B, Hosztafi S. Synthesis of Potential Haptens with Morphine Skeleton and Determination of Protonation Constants. Molecules, 2020,17, 4009.

Köteles I, Foroughbakhshfasaei M, Dobó M, Ádám M, Boldizsár I; Szabó ZI, Tóth G. (2020) Determination of the Enantiomeric Purity of Solriamfetol by High-Performance Liquid Chromatography in Polar Organic Mode Using Polysaccharide-Type Chiral Stationary Phases. Chromatographia, 2020, 83, 909-913.

Köteles I, Hosztafi S. Vaccines against Drug Abuse: Morphine-Hapten Design and Synthesis. Proceedings, 2019, 41, 48.

Köteles I. Kábítószer- és egyéb függőségek kialakulása és kezelési stratégiái. Gyógyszerészet, 2018, 62, 726-734.